The Science of Signals, The Promise of Cures

Advancing precision medicine with multiomics 
and AI-powered bioinformatics expertise

Diverse, multimodal omics data is the path to make the next breakthroughs in drug discovery & precision medicine

+70%

Multiomics integration increases biomarker discovery success rates by 70%

2.6x

Drug targets with genetic support are 2.6 times more likely to succeed in clinical trials 

-25%

Effective use of genomics and bioinformatics in drug development can reduce R&D costs by up to 25%

Leveraging cutting-edge multiomics technologies, advanced bioinformatics, and AI-driven insights, we transform complex biological data into actionable breakthroughs that accelerate drug development, diagnostics, and precision medicine

At Signios, we support genetic research for

Sequencing and multiomics solutions to drive discovery in genetic disease research.

Premade Library Sequencing

Premade Library Sequencing

RNA Sequencing

RNA Sequencing

Whole Genome Sequencing
Whole Genome Sequencing
Whole Exome Sequencing

Whole Exome Sequencing

Single-cell Sequencing
Single-cell Sequencing
Spatial Transcriptomics
Spatial Transcriptomics
Immune Repertoire Sequencing
Immune Repertoire Sequencing
Epigenomics Sequencing
Epigenomics Sequencing
Oncology Panel Sequencing
Oncology Panel Sequencing
Long-read Sequencing
Long-read Sequencing

Sequencing, multiomics, antibody engineering, and real-world evidence to improve discovery & development.

Identify targets using advanced multiomics technologies and powerful bioinformatics
Accelerate the production of antibodies with our high-throughput antibody engineering lab

Leverage real-world evidence (RWE) from global research networks across the US, Europe, Asia, Africa, Middle East, and Latin America.

Infrastructure and expertise for partners to develop, validate, and distribute Dx and CDx.

Complement your operations with Lab-in-the-cloud (LINC) modular dry-lab services

Leverage our experience & infrastructure for genomic assay development and validation
Bring your testing to our partner and distribution network in 30+ countries globally

Enhanced capabilities with advanced multiomics insights, robust data resources, and streamlined workflows.

Fast & reliable RNA sequencing, whole genome and exome sequencing, long-read sequencing, immune profiling, cancer panel sequencing
Automated, scalable workflows ensuring quick turnaround times and reliable data processing for large volumes of samples
Access to PhD-level scientists and multiomics experts who support everything from study design to data interpretation

Advancing Science in Critical Therapeutic Areas

Oncology

Sequencing capabilities allow for in-depth investigation into tumor genomics, tumor microenvironments, and molecular pathways driving cancer progression

Immunology

Immune profiling of single cells assist in studying immune system dynamics, immune responses, and the mechanisms of immune evasion in cancer

Rare Diseases

Whole genome and exome sequencing to enable discovery of novel genetic mutations and understanding the genetic basis of rare disorders

Neurology Disorders

Spatial biology aids in understanding the molecular underpinnings of neurodegenerative disorders, helping identify biomarkers and potential therapeutic targets
Population Health & Epidemiology

RWE supports epidemiological studies, population health research, and the development of inclusive therapies that address global health disparities

Pharmagenomics & Precision Medicine

Multiomics aids in identifying biomarkers for drug efficacy, safety, and dosage optimization, advancing personalized treatment strategies in various therapeutic areas

Our Customers

Many of the world’s leading academic and biopharmaceutical companies partner with Signios Bio to unlock deeper insights into the biology of disease and enable the future of precision medicine.
Here are just a few.

Our Capabilities

Signios Bio is a leading sequencing service provider based in Foster City, California, offering a wide range of gene and genome sequencing capabilities. Services include whole genome sequencing (WGS), whole exome sequencing (WES), immune repertoire sequencing, epigenomics, and long-read sequencing.

The Foster City laboratory is equipped with high-throughput platforms such as the Illumina NovaSeq X Plus, MiSeq, PacBio Revio, 10X Genomics Chromium, Visium Spatial, and the Sony MA900 Cell Sorter—supporting complex research applications across multiple domains.

Signios Bio also specializes in RNA-Seq, single-cell and spatial transcriptomics, and provides comprehensive bioinformatics analysis with every project. From data processing to customized reporting, the in-house team ensures accurate, actionable results.

Whether you’re looking for DNA sequencing services in the Bay Area or anywhere in the U.S., Signios Bio delivers the technology, expertise, and turnaround times needed to support complex research.

Signios By the Numbers

200+

peer-reviewed publications

1,000+

citations of our work

500,000+

DNA sequencing assays run

10M+

single-cells sequenced

17M+

Unique variants identified

250,000+

transcriptomes sequenced