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Large Scale Genomics Data Network

Diabetes Clinical knowledge base

As the market leader for genomic diagnostics in India, “the single most interesting country in terms of genetic diversity,” and as a founding member of the GenomeAsia100K, MedGenome has created an environment for genomic analysis unlike anywhere else in the world. We can offer unprecedented access to data that can unlock questions on biology of disease, and enable new therapies which will have global impact.

Our research platform enables genetic research studies into complex human diseases, otherwise intractable by conventional genetic analysis.

Enabling insights generation from large scale genomics research

  • Access to large cohorts of retrospective patient samples with matched clinical data
  • Access customized prospective cohorts
  • Capabilities in high-throughput sequencing and informatics capabilities

MedGenome’s genomics research platform offers infrastructure and service capabilities to enable large scale genomics research. MedGenome clients can leverage our collaborator network, rich data and research informatics for accelerating basic and drug discovery research.

  • Infrastructure

    Provides access to patient cohorts – biosamples,  genomics and rich clinical data;  continued access to patients for follow-up;  pedigree information

  • Services and Research Informatics

    Provides access to state-of-the-art sequencing and research informatics services;  knowledgebase solutions in focused disease areas

MedGenome has a network of over 45 large hospital collaborators and genetic centers that offer sample access with archived clinical data across the following disease areas.

Genomics research studies on stratified population substructures are found to be effective.

Various examples of discovery of disease genes using defined populations:

  • Hypercholesterolemia (LDL receptor)
  • Cancer (APC, RB)
  • Obesity (ABC1, PCSK9)
  • Diabetes (PPAR-γ )

Indian population genetics is a treasure trove of information and insights.

  • Indian population originated from a small number of founder families
  • Ancestral population became heterogeneous over time due to diverse climatic and other life style conditions
  • Restricted gene flow between groups created 3000 – 5000
  • Population isolates

GenomeAsia 100K

MedGenome is a founding member of GenomeAsia 100K, a non-profit consortium collaborating to sequence 100,000 Asian individuals’ genomes to help accelerate population specific medical advances and precision medicine.
The first stage of this project will be carried out by the sequencing of 10,000 genomes for ethnic stratification for within each local ancestry. This will be followed by the sequencing of the genomes of 90,000 individuals combined with clinical and phenotype information to find unique Asian variants. Then genomics and clinical ‘big data’ sets will be parsed to build upon currently available information on genetic diversity.

visit genomeasia 100k

Considering genomic research?

We’re at your service

Contact us today to discuss how MedGenome’s large scale population genomics can help further your research, and in the development of new therapies.
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