NGS Informatics

Areas of Expertise

Data analysis

  • Variant calling
  • Gene expression
  • T-cell neo-epitope identification
  • Tumor microenvironment analysis
  • Epigenetic regulation
  • Genotype – phenotype correlation
  • Gene signature analysis

Data sources

  • Mouse studies
  • Primates
  • Microbiome
  • Human preclinical and clinical trials

Data type

  • Whole Genome analysis
  • Exome
  • RNAseq
  • Chipseq
  • Methylseq
  • miRNA
  • Small RNA analysis
  • Microarray
  • Clinical

Disease areas

  • Oncology
  • Neurology
  • Cardiovascular
  • Diabetes
  • Ophthalmology
  • ENT
  • Autoimmune
  • Pre-natal
  • Rare diseases
  • Population Genomics/Longevity

Research Report Example*:

Head and Neck Cancer

T-cell neo-epitope Prediction

Report Sections:
  • Summary of exome and RNAseq data
  • QC matrix and data alignment
  • Variant calls and annotation
  • Expression of genes and variants
  • Correlation between exome and RNAseq data
  • Peptide generation and binding analysis
  • Identifying MHC-binding and TCR-binding peptides
  • Peptide processing and transport
  • List of prioritized T-cell neo-epitopes

Research Report Example*:

Differential Gene Expression Analysis

Report Sections:
  • Summary of RNAseq data
  • QC matrix and data alignment
  • Quantitation of gene expression
  • Comparison of expression between samples
  • Differentially expressed genes
  • Pathway analysis
  • Gene expression signature analysis
*Sample report available on request
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