ChIP-seq is a powerful method to map transcription factor binding sites and histone modification status on a genome-wide scale. This technique is a combination of chromatin immunoprecipitation assays with sequencing. Main steps in the ChIP-seq include cross-linking a protein to chromatin, shearing the chromatin, using a specific antibody to precipitate the protein of interest with its associated DNA, reverse cross linking and finally purifying the associated DNA fragments.

MedGenome has state-of-the-art Next Generation Sequencing Illumina platforms Miseq, Hiseq 4000 / 2500 and X10 at its facilities in Foster City, California and Bangalore, India.

Sitemap