Comprehensive RNA Sequencing solutions
MedGenome offers flexible library preparation options based on RNA quality and quantity allowing researchers to generate optimal quality data from their samples. We are able to work with RNA from all sources such as FFPE or low cell counts by leveraging highly optimized workflows and a consultative approach with customers to make informed decisions.
RNA sequencing services
| Library Prep Services | Assay Type | Stranded Type | Starting Material | Input Amount |
|---|---|---|---|---|
| TruSeq Stranded mRNA | mRNA Seq | Yes | RNA | 100 ng - 1 μg RNA |
| Illumina Stranded mRNA | mRNA Seq | Yes | RNA | 25 ng - 1 μg RNA |
| Takara SMART-Seq V4 | mRNA Seq | No | RNA, Cells | 10 pg - 10 ng RNA, 1 - 1,000 cells |
| TruSeq Stranded Total RNA | Total RNA | Yes | RNA | 100 ng - 1 μg RNA |
| Pico V2 / V3 | Total RNA | Yes | RNA | 250 pg - 10 ng RNA |
| SMART-Seq Stranded | Total RNA | Yes | RNA, Cells | 10 pg - 10 ng RNA, 1 - 1,000 cells |
RNA sequencing services
BioFX's transcriptome analysis platform was built using state-of-the-art analysis tools for gene expression, differential expression, pathway enrichment, splicing and fusion analysis and more.
A genomics-based approach to analyze the tumor microenvironment can provide unique insights beyond IHC and FACS methods. OncoPeptTUME deeply interrogates RNA-Seq data sets to produce high resolution mapping of the tumor microenvironment using proprietary cell type specific gene expression signatures. OncoPeptTUME provides a critical assessment of the inflammatory microenvironment that modulates T-cell infiltration and its anti-tumor activities to enable better prediction of treatment response and efficacy.
The OncoPepTUME pipeline quantifies the relative infiltration of innate and adaptive immune cells (CD8+, CD4+, T cells, B cells, Treg cells, NK cells, Macrophages, Monocytes, Neutrophils) with proprietary immune cell type-specific gene expression signatures. Identify biomarkers for patient selection, predict likelihood of response to checkpoint inhibitor therapies and monitor durability of response.
Our patented OncoPeptTUME algorithm analyzes RNA-Seq data to produce a high-resolution mapping of the tumor microenvironment using proprietary cell type specific gene expression signatures. This provides a critical assessment of the inflammatory microenvironment that modulates T-cell infiltration and its anti-tumor activities to enable better prediction of treatment response and efficacy.
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MedGenome's customer portal allows for easy sample submission and sample tracking during lab processing. Using our portal ensures data QC, raw data and interactive analysis reports are delivered securely.
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Submit documents and ship samples 
We process and analyze your samples 
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